Summary: In addition to updating each chapter and including a discussion of the new gaseous neuromodulators nitric oxide and carbon monoxide, the authors have made two major changes in this edition. A previous chapter on Metabolism in the Central Nervous System has been eliminated since they feel it has outlived its usefulness. However, some of the material from this chapter has been incorporated into a new chapter on the genetic basis of neurological and psychiatric diseases ...show more. With the almost biweekly discovery of genes that appear to be involved in diseases of the nervous system, this area has the potential for providing a revolutionary kind of therapy. The seven editions of this versatile text published over a quarter century attest to its value. It continues to be the first choice wherever courses focus on chemical neurotransmission or basic neuropharmacology : neuroscience courses in medical schools and at the undergraduate level, pharmacy schools, graduate pharmacology programs, and residency programs in psychiatry and neurology.
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