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Biochemistry - Text Only

Biochemistry - Text Only - 2nd edition

ISBN13: 978-0030223181

Cover of Biochemistry - Text Only 2ND 99 (ISBN 978-0030223181)
ISBN13: 978-0030223181
ISBN10: 0030223180
Cover type:
Edition/Copyright: 2ND 99
Publisher: Saunders College Division
Published: 1999
International: No

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Biochemistry - Text Only - 2ND 99 edition

ISBN13: 978-0030223181

Reginald H. Garrett and Charles M. Grisham

ISBN13: 978-0030223181
ISBN10: 0030223180
Cover type:
Edition/Copyright: 2ND 99
Publisher: Saunders College Division

Published: 1999
International: No
Summary

This beautifully and consistently illustrated text gives junior or senior science majors in an introductory course the most current presentation of biochemistry available. Written by a chemist and a biologist, the book presents biochemistry from balanced perspectives.

Key Features

  • Critical Developments in Biochemistry boxes pique student interest with information on new advances and technologies.
  • A Deeper Look boxes explore material more in-depth, such as historical information or special-interest topics.
  • Human Biochemistry boxes focus on topics related to medical biochemistry.
  • Chapter 3 on Bioenergetics presents fundamental thermodynamic relationships useful for understanding energetics of cellular metabolism.
  • In Chapters 5 and 6, and appearing throughout the rest of the book, a gallery of ribbon diagrams and space-filling computer graphics captures the diversity of biomolecules (developed at the University of Virginia).
  • Chapter 13, on recombinant DNA, illustrates the enormous power of this new tool to biochemical research.
  • Chapter 32 recounts the biochemical approaches that "cracked"the genetic code.
  • Chapter 34 pulls together an up-to-date perspective on the rapidly changing fields of cellular signaling, covering hormone action, oncogenes, neurological disorders, and many others.
  • Four-color molecular graphics developed specifically for the book give three dimension to many complex biomolecules. Color- coding of the molecules makes them easy to identify.
  • Sound pedagogy, including helpful in-text examples, end-of-chapter references and problems, contributes to students' mastery of the material.

New Features

  • Reorganization of chapters results in a single text with some chapters eliminated, several shortened, and some combined.
  • New "Critical Developments in Biochemistry," "Human Biochemistry" and "A Deeper Look" boxes include: A Fad Diet--Low Carbohydrates, High Protein, High Fat, Fool's Gold and the Reductive Citric Acid Cycle--The First Metabolic Pathway?, Melittin--How to Sting Like a Bee, Telomeres--A timely End to Chromosomes, and Knockout Mice: A Method to Investigate the Essentiality of the Gene.
  • About 20% of the text has been rewritten to increase the clarity of expression and to include new developments in biochemistry.
  • Much of the artwork is new or modified. Icons used in the previous edition for small molecules have been eliminated for a better over-all design.
  • Membrane Transport, formerly a chapter in the supplement, is now a chapter (10) in the text, making for a more logical link with the previous chapter (9) on membranes.
  • Introductory chapter on nucleic acids and recombinant DNA are now grouped together as Chapters 11-13 for a more cohesive presentation.
  • A new chapter (17) discusses proteins that turn chemical energy into the mechanics of movement.

Author Bio

Garrett, Reginald H. : University of Virginia


Grisham, Charles M. : University of Virginia

Table of Contents

I. Molecular Components of Cells

1. Chemistry is the Logic of Biological Phenomena
2. Water, pH, and Ionic Equilibria
3. Thermodynamics of Biological Systems
4. Amino Acids
5. Proteins: Their Biological Functions and Primary Structure
6. Proteins: Secondary, Tertiary, and Quaternary Structure
7. Carbohydrates
8. Lipids
9. Membranes and Cell Surfaces
10. Membrane Transport
11. Nucleotides and Nucleic Acids
12. Structure of Nucleic Acids
13. Recombinant DNA: Cloning and Creation of Chimeric Genes

II. Enzymes

14. Enzyme Kinetics
15. Enzyme Specificity and Regulation
16. Mechanisms of Enzyme Action
17. Molecular Motors

III. Metabolism and Its Regulations

18. Metabolism and Vitamins
19. Glycolysis
20. The Tricarboxylic Acid Cycle
21. Electron Transport and Oxidative Phosphorylation
22. Photosynthesis
23. Gluconeogenesis, Glycogen Metabolism, and the Pentose Phosphate Pathway
24. Fatty Acid Catabolism
25. Lipid Biosynthesis
26. Nitrogen Acquisition and Amino Acid Metabolism
27. Synthesis and Degradation of Nucleotides
28. Metabolic Integration and the Unidirectionality of Pathways

IV. Information Transfer

29. DNA: Generic Information, Recombination, and Mutation
30. DNA: Replication and Repair
31. Transcription and the Regulation of Gene Expression
32. The Genetic Code
33. Protein Synthesis and Degradation

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