Summary: With the addition of two new co-authors, Biochemistry takes a new direction, as it becomes the first text to fully reflect the revolution that has taken place in biomedical science in the past ten years, culminating in the human genome project. A key focus of the new edition is the unifying features of protein structure and function that have been revealed by the incredible progress in gene sequencing. Such features are highlighted in a way that will help students ma ...show morester the complex and intricate subject matter.
New to this Edition : Incorporation of Major Breakthroughs Throughout The Updated Biochemsitry includes coverage of numerous new developments (see annotated table of contents), including some that have clarified for the first time how certain biological systems work. These include:
--ATP Synthase Ch.18
--Ribosome Structure/Function Ch.25
--The Potassium Channel Ch.13
--The Calcium Pump Ch.13 (The potassium channel and calcium pulp together represent the first detailed view we have had of the mechanism of ion pumps)
--Olfaction and Taste Detection Ch.32 (In addition, results from human genome sequencing are integrated at many points in the book.)
Molecular Evolutionary Theme--The first biochemistry book to be published after the decoding of the human genome, Biochemistry 5/e uses the powerful concept of evolution as one of its organizing themes. It features:
--New chapters on "Biochemical Evolution" (Ch.2) and "Exploring Evolution" (Ch.7).
--New material on evolutionary relationships, highlighted by special icons.
--New emphasis in the metabolism chapters now emphasize commonalities among pathways, allowing students to apply material learned in one context to new contexts. (Chs.16, 18-19, 24, 25, 26)
More Chemical and Structural Insights, Introduced through specific discussions and illustrated with carefully crafted three-dimensional chemical structures. Each new example makes clear how chemistry provides an effective solution to biological problems.
--All chemical reactions have been rerendered by the authors for more precise structural realism.
--Molecular mechanisms with accompanying illustrations have been added to the same metabolism chapters - mechanisms of particular importance to understanding biological function. (Chs. 16, 17, 24, 25)
Entire Art Program Redrawn by the Authors Specific changes include:
--All molecular diagrams recreated by Jeremy Berg for clearer and more consistent presentations of structure throughout.
--More pathway overview diagrams in the metabolism chapters, providing student with roadmaps to metabolic pathways. (Chs. 16-26)
--Art program expanded by nearly 20 % over the previous edition
Improved Pedagogy allows for better student understanding. The Fifth Edition features:
--Chapter-opening outlines, end-of-chapter summaries with new headings, and lists of key terms. All reinforce key concepts.
--Special icons highlight evolutionary coverage, clinically relevant material, or related media content on the Web.
--New overview diagrams provide students with a roadmap to metabolic pathways.
--Expanded end-of-chapter problems sets with almost 50 % more problems
--Four new types of problems
1. Data Interpretation Problems ask students to work with real experimental data presented in a table or graph.
2. Chapter Integration Problems require students to synthesize material from different parts of the book.
3. Media Problems refer students to specific interactive tutorials on the book's Web Site.
4. Mechanism Problems have students propose in detail a mechanism for a specific reaction. ...show less
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