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Bioinformatics

Bioinformatics - 3rd edition

ISBN13: 978-1904842163

Cover of Bioinformatics 3RD 07 (ISBN 978-1904842163)
ISBN13: 978-1904842163
ISBN10: 190484216X
Cover type:
Edition/Copyright: 3RD 07
Publisher: Scion Publishing Limited
Published: 2007
International: No

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Bioinformatics - 3RD 07 edition

ISBN13: 978-1904842163

Paul H. Dear

ISBN13: 978-1904842163
ISBN10: 190484216X
Cover type:
Edition/Copyright: 3RD 07
Publisher: Scion Publishing Limited

Published: 2007
International: No
Summary

Bioinformatics: Methods Express is unique . It is a book on bioinformatics that makes sense to non-bioinformaticians.

Bioinformatics: Methods Express helps you answer common questions such as:

*what else is similar to my gene?
*does this protein have any transmembrane regions?
*how do I visualize an alignment between these DNAs?
*where can I find specific transcription factor sequences?

The book provides the clear advice and explicit protocols that non-bioinformaticians need in order to understand what to do - and how to avoid common pitfalls. Each chapter guides you through the major databases and tools with worked examples - all accompanied by sample data files available online.

Topics covered include:
*data access
*sequence searches and alignments
*identification and annotation of features
*the transcriptome
*protein structure and function
*comparisons and phylogeny

Bioinformatics: Methods Express is a comprehensive manual for all wet-bench scientists who need to use bioinformatics - from postgraduate student to principal investigator.

Table of Contents

INTRODUCTION ( Paul H. Dear)

ACCESSING THE AVAILABLE DATA


1. Database resources (Neil Hall)

2. Navigating sequenced genomes (Melody Clark and Thomas Schlitt)

3. Sequence similarity searches (Ian Korf)


IDENTIFICATION AND ANNOTATION OF FEATURES


4. Identification and masking of repeats (Arian Smit)

5. Gene prediction (Marie-Adele Rajandream)

6. Prediction of non-coding transcripts (Alex Bateman)

7. Finding regulatory elements in DNA sequence (Debraj GuhaThakurta and Gary Stormo)

8. Expressed sequence tags (Arthur Gruber)


INFERRING PROTEIN STRUCTURE AND FUNCTION


9. Protein structure and its prediction (Arthur Lesk)

10. Gene ontology and protein functional classification ( Vineet Sangar)

11. Prediction of protein function (Rodrigo Lopez)


COMPARISONS AND PHYLOGENY


12. Inferring phylogenetic relationships from sequence data (Peter Foster)

13. Sequence alignment (Burkhard Morgenstern)


Index
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