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Bioinformatics : Sequence and Genome Analysis

Bioinformatics : Sequence and Genome Analysis - 01 edition

ISBN13: 978-0879696085

Cover of Bioinformatics : Sequence and Genome Analysis 01 (ISBN 978-0879696085)
ISBN13: 978-0879696085
ISBN10: 0879696087
Cover type: Paperback
Edition/Copyright: 01
Publisher: Cold Spring Harbor Laboratory Press
Published: 2001
International: No

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Bioinformatics : Sequence and Genome Analysis - 01 edition

ISBN13: 978-0879696085

David W. Mount

ISBN13: 978-0879696085
ISBN10: 0879696087
Cover type: Paperback
Edition/Copyright: 01
Publisher: Cold Spring Harbor Laboratory Press

Published: 2001
International: No
Summary

The application of computational methods to DNA and protein science is a new and exciting development in biology. Bioinformatics: Sequence and Genome Analysis is a comprehensive introduction to this emerging field of study. The book has many unique and valuable features:

  • It is written for any biologist who wants to understand methods of sequence and structure analysis and how the necessary computer programs work
  • Sequence alignment, structure prediction, phylogenetic and gene prediction, database searching, and genome analysis are clearly explained and amply illustrated
  • Underlying algorithms and assumptions are clearly explained for the non-specialist
  • Examples are presented in simple numerical terms rather than complex formulas and notation
  • Theoretical underpinnings are linked to biological problems and their solutions
  • Extensive tables provide descriptions and Web sources for a broad range of publicly available software
  • An associated Website (www.BioinformaticsOnline.org), accessible free of charge by book purchasers, provides links to Internet sources referred to in the text, as well as problem sets for classroom use, and other useful material not included in the text.


Based on the author's extensive experience as a molecular geneticist and bioinformaticist at the University of Arizona, this is a uniquely educational book, ideal as a laboratory reference for investigators and also as teaching reference for graduate and undergraduate students studying this fast-changing discipline.

Author Bio

Mount, David W. : University of Arizona, Tucson

Table of Contents

Preface
Chapter 1. Historical Introduction and Overview
Chapter 2. Collecting and Storing Sequences in the Laboratory
Chapter 3. Alignment of Pairs of Sequences
Chapter 4. Multiple Sequence Alignment
Chapter 5. Prediction of RNA Secondary Structure
Chapter 6. Phylogenetic Prediction
Chapter 7. Database Searching for Similar Sequences
Chapter 8. Gene Prediction
Chapter 9. Protein Classification and Structure Prediction
Chapter 10. Genome Analysis
Glossary
Index