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Classics in Total Synthesis II : More Targets, Strategies, Methods - With CD (Cloth)

Classics in Total Synthesis II : More Targets, Strategies, Methods - With CD (Cloth) - 03 edition

ISBN13: 978-3527306855

Cover of Classics in Total Synthesis II : More Targets, Strategies, Methods - With CD (Cloth) 03 (ISBN 978-3527306855)
ISBN13: 978-3527306855
ISBN10: 3527306854
Cover type:
Edition/Copyright: 03
Publisher: John Wiley & Sons, Inc.
Published: 2003
International: No

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Classics in Total Synthesis II : More Targets, Strategies, Methods - With CD (Cloth) - 03 edition

ISBN13: 978-3527306855

K. C. Nicolaou and S. A. Snyder

ISBN13: 978-3527306855
ISBN10: 3527306854
Cover type:
Edition/Copyright: 03
Publisher: John Wiley & Sons, Inc.

Published: 2003
International: No
Summary

Classics in Total Synthesis II is the long awaited sequel to Classics in Total Synthesis, a book that has made its mark as a superb tool for educating students and practitioners alike in the art of organic synthesis since its introduction in 1996. In this highly welcomed new volume, K.C. Nicolaou and Scott A. Snyder discuss in detail the most impressive accomplishments in natural product total synthesis during the 1990s and the first years of the 21st century. While all of the features that made the first volume of Classics so popular and unique as a teaching tool have been maintained, in this new treatise the authors seek to present the latest techniques and advance in organic synthesis as they beautifully describe the works of some of the most renowned synthetic organic chemists of out time.

  • domino reactions, cascade sequences, biomimetic strategies, and asymmetric catalysis are systematically developed through the chosen synthesis
  • cutting edge synthetic technologies are discussed in terms of mechanism and scope
  • new reactions, such as olefin metathesis, are presented in mini-review style
  • abundant references are given for further reading

Graduate students, educators, and researchers in the fields of synthetic and medicinal chemistry will wish to have a copy of this book in their collection as an indispensable companion that both augments and supplements the original Classics in Total Synthesis.

Author Bio

K.C. Nicolaou is Professor of Chemistry at the University of California, San Diego and is Chairman of the Department of Chemistry and holds the Skaggs Professorship of Chemical Biology and the Darlene Shiley Chair in Chemistry at The Scripps Research Institute. His impact on chemistry, biology and medicine flows from his works in chemical synthesis and chemical biology described in over 550 publications and 55 patents. For his contributions to research and education, he was elected a Member of the National Academy of Science, USA, a Fellow of the American Academy of Arts and Sciences, and a Foreign Member of the Academy of Athens, Greece, and received numerous prizes, awards and honors.

Scott A Snyder received his B.A. degree in Chemistry from Williams College in 1999, and then began graduate studies at The Scripps Research Institute under the guidance of Prof. K.C. Nicolaou. He is the recipient of a Barry M. Goldwater Fellowship in Science and Engineering, a National Science Foundation Predoctoral Fellowship, and a Graduate Fellowship from Pfizer, Inc.

Table of Contents

Chapter 1. Introduction: Perspectives in Total Synthesis.
Chapter 2. Isochrysohermidin (D.L. Boger).
Chapter 3. Swinholide A (I. Paterson).
Chapter 4. Dynemicin A (A.G. Myers and S.J. Danishefsky).
Chapter 5. Ecteinascidin 743 (E.J. Corey).
Chapter 6. Resiniferatoxin (P.A. Wender).
Chapter 7. Epothilones A and B (K.C. Nicolaou).
Chapter 8. Manzamine A (J.D. Winkler and S.F. Martin).
Chapter 9. Vancomycin (K.C. Nicolaou and D.A. Evans).
Chapter 10. Everninomicin 13,384-1 (K.C. Nicolaou).
Chapter 11. Bisorbicillinoids (K.C. Nicolaou).
Chapter 12. Aspidophytine (E.J. Corey).
Chapter 13. CP-Molecules (K.C. Nicolaou).
Chapter 14. Colombiasin A (K.C. Nicolaou).
Chapter 15. Quinine (G. Stork).
Chapter 16. Longithorone A (M.D. Shair).
Chapter 17. (--)-FR182877 (E.J. Sorensen).
Chapter 18. Vinblastine (T. Fukuyama).
Chapter 19. Quadrigemine C and Psycholeine (L.E. Overman)
Chapter 20. Diazonamide A (K.C. Nicolaou).
Chapter 21. Plicamine (S.V. Ley).
Chapter 22. Okaramine N (E.J. Corey).
Author Index.
Subject Index

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