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Essential Bioinformatics

Essential Bioinformatics - 06 edition

ISBN13: 978-0521840989

Cover of Essential Bioinformatics 06 (ISBN 978-0521840989)
ISBN13: 978-0521840989
ISBN10: 0521840988
Cover type:
Edition/Copyright: 06
Publisher: Cambridge University Press
Published: 2006
International: No

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Essential Bioinformatics - 06 edition

ISBN13: 978-0521840989

Jin Xiong

ISBN13: 978-0521840989
ISBN10: 0521840988
Cover type:
Edition/Copyright: 06
Publisher: Cambridge University Press

Published: 2006
International: No
Summary

Essential Bioinformatics is a concise yet comprehensive textbook of bioinformatics, which provides a broad introduction to the entire field. Written specifically for a life science audience, the basics of bioinformatics are explained, followed by discussions of the state-of-the-art computational tools available to solve biological research problems. All key areas of bioinformatics are covered including biological databases, sequence alignment, genes and promoter prediction, molecular phylogenetics, structural bioinformatics, genomics and proteomics. The book emphasizes how computational methods work and compares the strengths and weaknesses of different methods. This balanced yet easily accessible text will be invaluable to students who do not have sophisticated computational backgrounds. Technical details of computational algorithms are explained with a minimum use of mathematical formulae; graphical illustrations are used in their place to aid understanding. The effective synthesis of existing literature as well as in-depth and up-to-date coverage of all key topics in bioinformatics make this an ideal textbook for all bioinformatics courses taken by life science students and for researchers wishing to develop their knowledge of bioinformatics to facilitate their own research.

  • Concise yet comprehensive and written specifically for life scientists and those without a sophisticated computational background
  • Provides annotated guides to the most frequently used internet tools for each topic and discusses the advantages of different methods
  • Includes 6 step-by-step protocols for internet-based exercises to aid student's problem-solving skills using freely available bioinformatics tools
  • Glossary provides clear definitions and easy understanding of key bioinformatics concepts and tools

Table of Contents

Preface
Part I. Introduction and Biological Databases

1. Introduction
2. Introduction to biological databases

Part II. Sequence Alignment

3. Pairwise sequence alignment
4. Database similarity search
5. Multiple sequence alignment
6. Profiles and hidden Markov models
7. Protein motifs and patterns

Part III. Gene and Promoter Prediction

8. Gene prediction
9. Promoter and regulatory element prediction

Part IV. Molecular Phylogenetics

10. Phylogenetics basics
11. Phylogenetic tree construction methods and programs

Part V. Protein Structure Basics

13. Protein structure visualization, comparison and classification
14. Protein secondary structure prediction
15. Protein tertiary structure prediction
16. RNA structure prediction

Part VI. Genomics and Proteomics

17. Genome mapping, assembly and comparison
18. Functional genomics
19. Proteomics

Practical exercises
Glossary.

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