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Foye's Principles of Medicinal Chemistry - With CD

Foye's Principles of Medicinal Chemistry - With CD - 5th edition

ISBN13: 978-0781744430

Cover of Foye
ISBN13: 978-0781744430
ISBN10: 0781744431
Cover type:
Edition/Copyright: 5TH 02
Publisher: LeaFebiger
Published: 2002
International: No

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Foye's Principles of Medicinal Chemistry - With CD - 5TH 02 edition

ISBN13: 978-0781744430

David A. Williams, William O. Foye and Thomas L. Lemke

ISBN13: 978-0781744430
ISBN10: 0781744431
Cover type:
Edition/Copyright: 5TH 02
Publisher: LeaFebiger

Published: 2002
International: No
Summary

This comprehensive Fifth Edition has been fully revised and updated to meet the changing curricula of medicinal chemistry courses. The new emphasis is on pharmaceutical care that focuses on the patient, and on the pharmacist a therapeutic clinical consultant, rather than chemist. Approximately 45 contributors, respected in the field of pharmacy education, augment this exhaustive reference. New to this edition are chapters with standardized formats and features, such as Case Studies, Therapeutic Actions, Drug Interactions, and more. Over 700 illustrations supplement this must-have resource.

Table of Contents

Introduction: Origins of Medicinal Chemistry

Part I Principles of Drug Discovery

Overview: Drug Design and Development: A Perspective
1 Natural Products
2 Drug Design and Relationship of Functional Groups to Pharmacologic Activity
3 Molecular Modeling and Drug Design
4 Receptors and Drug Action
5 Drug Design Through Enzyme Inhibition
6 Peptide and Protein Drugs
7 Physicochemical and Biopharmaceutical Properties of Drug Substances and Pharmacokinetics
8 Drug Metabolism
9 U.S. Drug Regulation: An Overview

Part II Pharmacodynamic Agents

Overview: Drug Receptors: A Perspective
10 Drugs Affecting Cholinergic Neurotransmission
11 Drugs Affecting Adrenergic Neurotransmission
12 Serotonin Receptors and Drugs Affecting Serotonergic Neurotransmission
13 Local Anesthetics
14 Volatile Anesthetics
15 Hypnotics
16 Antiseizure Drugs
17 Psychotherapeutic Drugs: Antipsychotic and Anxiolytic Agents
18 Hallucinogens, Stimulants, and Related Drugs of Abuse
19 Opioid Analgesics
20 Drugs Used to Treat Neuromuscular Disorders: Antiparkinsonian and Spasmolytic Agents
21 Cardiac Agents: Cardiac Glycosides, Antianginal, and Antiarrhythmic Drugs
22 Diuretics
23 Angiotensin Converting Enzyme Inhibitors, Antagonists and Calcium Blockers
24 Central and Peripheral Sympatholytics and Vasodilators
25 Antihyperlipoproteinemics and Inhibitors of Cholesterol Biosynthesis
26 Antithrombotics, Thrombolytics, Coagulants and Plasma Extenders
27 Insulin and Oral Hypoglycemic Drugs
28 Adrenocorticoids
29 Estrogen, Progestins and Androgens
30 Thyroid Function and Thyroid Drugs
31 Calcium Homeostasis
32 Nonsteroidal Anti-Inflammatory Agents
33 Antihistamines and Related Antiallergic and Antiulcer Agents
34 Antibiotics and Antimicrobial Agents
35 Antiparasitic Agents
36 Antifungal Drugs
37 Antimycobacterial Agents
38 Cancer and Cancer Chemotherapy
39 Antiviral Agents and Protease Inhibitors

Part III Recent Advances in Drug Discovery

40 Pharmaceutical Biotechnology
41 Gene Therapy
42 Antisense Therapeutic Agents
43 Selective Estrogen Receptor Modulators

pKa Values for Some Drugs and Miscellaneous Organic Acids and Bases; pH Values for Tissue Fluids

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