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Genetics : A Conceptual Approach

Genetics : A Conceptual Approach - 03 edition

ISBN13: 978-1572591608

Cover of Genetics : A Conceptual Approach 03 (ISBN 978-1572591608)
ISBN13: 978-1572591608
ISBN10: 1572591609
Cover type: Paperback
Edition/Copyright: 03
Publisher: W.H. Freeman
Published: 2003
International: No

List price: $108.50

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Genetics : A Conceptual Approach - 03 edition

ISBN13: 978-1572591608

Benjamin A. Pierce

ISBN13: 978-1572591608
ISBN10: 1572591609
Cover type: Paperback
Edition/Copyright: 03
Publisher: W.H. Freeman

Published: 2003
International: No
Summary

Designed for introductory genetics courses, Genetics: A Conceptual Approach focuses on the important concepts and mechanics of genetics, guiding students toward seeing the big picture without overwhelming them with detail. Drawing on more than twenty years of teaching experience, Benjamin Pierce brings the material to life by making important connections between topics, by providing advice and encouragement at difficult places, and describing people, places, and cornerstone experiments.

Features :

  • By continually connecting major concepts to one another, Genetics helps students navigate their way through the subject. Concepts are clearly illustrated and reinforced across sections within chapters, at the ends of chapters, and across chapters. (see pp. 52, 464, 673-7)

  • In-Chapter Worked Problems that provide students with step-by-step solutions. Each chapter contains one or more of these walk through problems. Worked problems also appear at the end of each chapter. (see pp. 64-5, 675-6)

  • Fresh, Original Problem Sets, thoroughly class-tested for accuracy. No other genetics text has the quality, quantity, and sheer variety of problems. (see pp. 73-4, problems 24 & 31; pp. 468-9, problems 18, 20, 21-5)

  • "The New Genetics: Mining Genomes" tutorials, current, interactive web-based exercises that guide students through analyses and searches on the genomic databases that professional geneticists use.

  • A superior art program with supremely clear, simple illustrations. In many instances, the art walks the student through a biological process step by step. Many figures contain a statement of the take-home message in the form of a Conclusion. (see p. 53, fig. 3.5, p. 443, fig 16.7)

  • Integrated Media--Each chapter in the text contains several web icons that point students to the web site, which features interactive exercises, colorful animations, and additional information.


Author Bio

Pierce, Benjamin : Baylor University

Table of Contents

1. Introduction to Genetics
Royal Hemophilia and Romanov DNA
The Importance of Genetics
Brief History of Genetics
Basic Concepts in Genetics

2. Chromosomes and Cellular Reproduction
The Diversity of Life
Basic Cell Types
Cell Reproduction
Sexual Reproduction and Genetic Variation

3. Basic Principles of Heredity
Black Urine and First Cousins
Mendel, The Father of Genetics
Monohybrid Crosses
Connecting Concepts: Connecting Genetic Crosses With Meiosis
Connecting Concepts: Ratios in Simple Crosses
Crosses Involving Multiple Loci
Observed and Expected Ratios

4. Sex Determination and Sex-Linked Characteristics
The Toothless, Hairless Men of Sind
Sex Determination
Sex-Linked Characteristics
Connecting Concepts: Recognizing Sex-linked Inheritance

5. Extensions and Modifications of Basic Principles
Was Mendel Wrong?
Dominance Revisited
Lethal Alleles
Multiple Alleles
Gene Interaction
Connecting Concepts: Interpreting Ratios Produced by Gene Interaction
The Interaction of Sex and Heredity
Anticipation
Interaction of Genes and Environment

6. Pedigree Analysis and Application
Lou Gehrig and Superoxide Free Radicals
The Study of Genetic Characteristics in Humans
Pedigrees
Twin Studies
Adoption Studies
Genetic Counseling and Genetic Testing

7. Linked Genes and Recombination
Alfred Sturtevant and the First Genetic Map
Genes That Assort Independently and Those That Don't
Linkage and Recombination Between Two Genes
Connecting Concepts: Relating Independent Assortment, Linkage, and Crossing Over
Linkage and Recombination between Three Genes
Connecting Concepts: Stepping Through the Three-point Cross
Physical Chromosome Mapping

8. Bacterial and Viral Genetics
The Sverdlovsk Anthrax Outbreak of 1979
Bacterial Genetics
Viral Genetics

9. Chromosome Variations
Once in a Blue Moon
Chromosome Variation
Chromosome Rearrangements
Aneuploidy
Polyploidy
Chromosome Mutations and Cancer

10. DNA and the Chemical Nature of the Gene
The Elegantly Stable Double Helix
Characteristics of Genetic Material
The Molecular Basis of Heredity
The Structure of DNA
Connecting Concepts: Genetic Implications of DNA Structure
Special Secondary Structures in DNA and RNA

11. Chromosome Structure and Organization, Transposable Elements
YACs and the Common Mouse
Packing DNA Into Small Spaces
The Bacterial Chromosome
The Eukaryotic Chromosome
Variation in DNA Sequences of Eukaryotes
Types of DNA Sequences in Eukaryotes
Transposable Elements
Transposition
The Nature of Transposable Elements
Connecting Concepts: Classes of Transposable Elements
The Role of Transposable Elements

12 DNA REPLICATION AND RECOMBINATION
The Cause of Bloom Syndrome
The Central Problem of Replication
Semiconservative Replication
The Mechanism of Replication
Connecting Concepts: The Basic Rules of Replication
Late Night Inspiration--the Polymerase Chain Reaction
The Molecular Basis of Recombination

Chapter 13 TRANSCRIPTION
RNA in the Primeval World
RNA Molecules
Transcription: Synthesizing RNA from a DNA Template
The Process of Prokaryotic Transcription
Connecting Concepts: The Basic Rules of Transcription
The Process of Eukaryotic Transcription

Chapter 14 RNA MOLECULES AND RNA PROCESSING
The Immense Dystrophin Gene
Gene Structure
Messenger RNA
Connecting Concepts - Eukaryotic Gene Structure and pre-mRNA Processing
Transfer RNA
Ribosomal RNA

Chapter 15 THE GENETIC CODE AND TRANSLATION
Lesch-Nyhan Syndrome and the Relationship of Genotype and Phenotype
The Molecular Relationship of Genotype and Phenotype
The Genetic Code
The Process of Translation

Chapter 16 CONTROL OF GENE EXPRESSION
Creating Giant Mice With Gene Regulation
General Principles of Gene Regulation
Gene Regulation in Prokaryotic Cells
Eukaryotic Gene Regulation
Connecting Concepts: Comparison of Prokaryotic and Eukaryotic Gene Control

Chapter 17 GENE MUTATIONS AND DNA REPAIR
The Genetic Legacy of Chernobyl
The Nature of Mutations
Causes of Mutations
The Study of Mutations
DNA Repair

Chapter 18 RECOMBINANT DNA TECHNOLOGY
PCR and the Arrival of Tuberculosis in America
Basic Concepts in Recombinant DNA Technology
Recombinant DNA Techniques
Applications of Recombinant DNA Technology

Chapter 19 GENOMICS
The Decaying Genome of Mycobacterium leprae
Structural Genomics
Physical Maps
Functional Genomics
Comparative Genomics
The Future of Genomics

Chapter 20 ORGANELLE DNA
Coyote Genes in Declining Wolves
The Biology of Mitochondria and Chloroplasts
Structure of Mitochondria and Chloroplasts
Mitochondrial DNA
Chloroplast DNA
Connecting Concepts: Genome Comparisons
Intergenomic Exchange of Genetic Information

Chapter 21 DEVELOPMENTAL GENETICS, IMMUNOGENETICS, AND CANCER GENETICS
Flies With Extra Eyes
Developmental Genetics
Connecting Concepts: Control of Development
Immunogenetics
Cancer Genetics

Chapter 22 QUANTITATIVE GENETICS
Winning Thoroughbreds Through Quantitative Genetics
Quantitative Traits
Statistical Methods for Analyzing Quantitative Traits
Heritability
Response to Selection

Chapter 23 POPULATION AND EVOLUTIONARY GENETICS
The Genetic History of Tristan da Cuna
Genetic Variation
Comparison of Observed Genotypic Frequencies With Those
Nonrandom Mating
Connecting Concepts: The General Effects of Evolutionary Forces
Molecular Evolution


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