Introduction To Genetic Analysis - 10th edition

Anthony Griffiths is Professor Emeritus at the University of British Columbia, where he taught Introductory Genetics for 35 years. The challenges of teaching that course have led to a lasting interest in how students learn genetics. His research interests center on the developmental genetics of fungi, using the model fungus Neurospora crassa. He also loves to dabble in the population genetics of local plants. Griffiths was President of the Genetics Society of Canada from 1987 to 1989, receiving its Award of Excellence in 1997. He has recently served two terms as Secretary-General of the International Genetics Federation.

Susan Wessler is Regents Professor of Plant Biology at the University of Georgia, where she has been since 1983. She teaches courses in introductory biology and plant genetics to both undergraduates and graduate students. Her interest in innovative teaching methods led to her selection as a Howard Hughes Medical Institute Professor in 2006. She is coauthor of The Mutants of Maize (Cold Spring Harbor Laboratory Press) and of more than 100 research articles. Her scientific interest focuses on the subject of transposable elements and the structure and evolution of genomes. She was elected to membership in the National Academy of Sciences in 1998.

Richard Lewontin is the Alexander Agassiz Research Professor at Harvard University. He has taught genetics, statistics and evolution at North Carolina State University, the University of Rochester, the University of Chicago and Harvard University. His chief area of research is population and evolutionary genetics; he introduced molecular methods into population genetics in 1966. Since then, he has concentrated on the study of genetic variation in proteins and DNA within species. Dr. Lewontin has been President of the Society for the Study of Evolution, the American Society of Naturalists, and the Society for Molecular Biology and Evolution, and for some years, he was coeditor of The American Naturalist.

Sean Carroll is Professor of Molecular Biology and Genetics and Investigator with the Howard Hughes Medical Institute at the University of Wisconsin-Madison, where he teaches genetics and evolutionary developmental biology. Dr. Carroll's research has centered on genes that control body patterns and play major roles in the evolution of animal diversity. He is the author of the several books, including The Making of the Fittest (2006, W.W. Norton) and Endless Forms Most Beautiful: The New Science of Evo Devo (2005, W.W. Norton). The latter was a finalist for the 2005 Los Angeles Times Book Prize (Science and Technology) and the 2006 National Academy of Sciences Communication Award. He is also co-author with Jen Grenier and Scott Weatherbee of the textbook From DNA to Diversity: Molecular Genetics and the Evolution of Animal Design (2nd ed; Blackwell Scientific) and the author or coauthor of more than 100 research articles.

1. Genetics and the Organism

PART I: TRANSMISSION GENETIC ANALYSIS
2. Patterns of Inheritance
3. The Chromosomal Basis of Inheritance
4. Eukaryote Chromosome Mapping by Recombination
5. The Genetics of Bacteria and Their Viruses

PART II: THE RELATIONSHIP OF DNA AND PHENOTYPE
6. From Gene to Phenotype.
7. DNA: Structure and Replication
8. RNA: Transcription and Processing
9. Proteins and Their Synthesis
10. Regulation of Gene Transcription

PART III: GENOME STRUCTURE AND ENGINEERING
11. Gene Isolation and Manipulation
12. Genomics
13. The Dynamic Genome: Transposable Elements

PART IV: THE NATURE OF HERITABLE CHANGE
14. Mutation, Repair, and Recombination
15. Large-Scale Chromosomal Changes

PART V: FROM GENES TO PROCESSES
16. Dissection of Gene Function
17. Genetic Regulation of Cell Number: Normal and Cancer Cells
18. The Genetic Basis of Development

PART VI: THE IMPACT OF GENETIC VARIATION
19. Population Genetics
20. Quantitative Genetics
21. Evolutionary Genetics

A Brief Guide to Model Organisms Appendix A: Genetic Nomeclature Appendix B: Bioinformatics Resources for Genetics and Genomics Glossary Answers to Selected Problems Index