Molecular Biology Of The Cell - With Cd - 4th edition

Alberts, Bruce :

Bruce Alberts received his Ph.D. from Harvard University and spent 30 years as a Professor of Biochemistry - first at Princeton University and then at the University of California, San Francisco. His research interests focused on the protein machines that replicate DNA. Since 1993, he has served as the President of the National Academy of Sciences in Washington, D.C. One of his major goals at the Academy has been to change the nature and extent of the science education received by every student in the United States, starting with children 5 years old and continuing through the college years.

Johnson, Alexander : University of California, San Francisco

Alexander Johnson received his Ph.D. from Harvard University and is now a Professor at the University of California, San Francisco, where he teaches molecular biology to medical, pharmacy, dentistry, and graduate students. His research interests include the mechanisms used by cells to switch their genes on and off, as well as the molecular genetics of Candida albicans, a human fungal pathogen.

Lewis, Julian :

Julian Lewis did his D.Phil. in physics at the University of Oxford and then, after a postdoctoral year in Russia, switched to developmental biology, working in the laboratory of Lewis Wolpert in London. He moved on to King's College London, where for eight years he taught medical students. He is currently a Principal Scientist at the Imperial Cancer Research Fund, with research interests in the development of sense organs and in the role of the Notch signaling pathway in controlling the fine-grained patterns of cell types that form the tissues of the vertebrate body.

Raff, Martin : University College London

Martin Raff was born and educated in Montreal. He received his BSc and MD degrees at McGill University and did a residency in medicine at the Royal Victoria Hospital in Montreal and in neurology at the Massachusetts General Hospital in Boston. He did postdoctoral training in immunology at the National Institute for Medical Research in London, after which he moved to University College London, where he has been a Professor of Biology since 1979. He is currently at the Medical Research Council Laboratory for Molecular Cell Biology and Cell Biology Unit and in the Biology Department at University College London. His research has been in immunology, cell biology, and developmental neurobiology. He is a Fellow of the Royal Society and the Academia Europaea, a foreign member of the American Academy of Arts and Sciences, was president of the British Society of Cell Biology from 1991 to 1995, and is currently Chairman of the UK Life Sciences Committee.

Roberts, Keith :

Keith Roberts did his degree and Ph.D. in biochemistry at the University of Cambridge. He then moved to the John Innes Centre in Norwich where for 16 years he was Head of the Department of Cell Biology. He is currently Associate Research Director and his scientific interest is in plant biology, with a particular focus on the functional architecture of the plant cell wall and its role in plant growth and development. He maintains an active interest in science education in schools.

Walter, Peter : University of California, San Francisco

Peter Walter grew up in Berlin, Germany. He received his Ph.D. from The Rockefeller University in New York for studies with Nobel laureate Günter Blobel. He is currently an Investigator of the Howard Hughes Medical Institute and Professor and Chairman of the Department of Biochemistry and Biophysics at the University of California at San Francisco. His research program concerns fundamental questions in molecular cell biology, such as the mechanisms of how proteins are sorted and moved across membranes, how membrane fusion is regulated, and how cells adjust the abundance of intracellular organelles according to need.

"I found both the writing and the illustrations to be excellent - clear, up-to-date and accurate."

--Harry Noller, University of California, Santa Cruz, USA, Commenting on Chapter 6

"[The] chapter on gene expression was terrific - I was amazed at how I would write down a comment and then a page or so later see that it was covered."

--Mike Carey, University of California, Los Angeles, USA, Commenting on Chapter 7

"It is thrilling to think that medical students in the future may arrive with some grasp of this complex material. I think the overall layout of the chapter is excellent."

--Clay Armstrong, University of Pennsylvania, USA, Commenting on Chapter 11

"I enjoyed reading the chapter very much. It's comprehensive, clear and easy to read."

--Lily Jan, University of California, San Francisco, USA, Commenting on Chapter 11

"I think this chapter is excellent and represents a lot of work!"

--Jennifer Lippincott-Schwartz, National Institutes of Health, Bethesda, USA, Commenting on Chapter 11

"What I read was excellent: easy to read, and an appropriate and judicious balance of concepts, generalizations, and facts that provide a fundamental understanding without getting bogged down in too many details and vocabulary. The illustrations were also excellent and appropriate."

--Arthur E. Johnson, Texas A&M University College of Medicine, USA, Commenting on Chapter 12

"I found the chapter quite excellent and right up-to-date, covering the main recent developments, in particular the relevant membrane protein structures, in sufficient detail to explain all important concepts in molecular bioenergetics."

--Werner Kühlbrandt, Max-Planck-Institut für Biophysik, Germany, Commenting on Chapter 14

"I think [the chapter] reads very well, and makes a complex subject readily accessible."

--Tony Pawson, Samuel Lunefeld Research Institute, Canada, Commenting on Chapter 15

"I have read the section carefully several times and I think it is very good. This chapter is very well written and covers many aspects of this complex problem."

--Frank Gertler, Massachusetts Institute of Technology, USA, Commenting on Chapter 16

"This is a very well-written, clear and fun piece to read. I found the explanations helpful and insightful."

--Laura Machesky, University of Birmingham, UK, Commenting on Chapter 16

Garland Science Web Site, April, 2002

I. Introduction to the Cell
Chapter 1 Cells and Genomes
Chapter 2 Cell Chemistry and Biosynthesis
Chapter 3 Proteins

II. Basic Genetic Mechanisms
Chapter 4 DNA and Chromosomes
Chapter 5 DNA Replication, Repair, and Recombination
Chapter 6 How Cells Read The Genome: From DNA to Protein
Chapter 7 Control of Gene Expression

III. Methods
Chapter 8 Manipulating Proteins, DNA, and RNA
Chapter 9 Visualizing Cells

IV. Internal Organization of the Cell
Chapter 10 Membrane Structure
Chapter 11 Membrane Transport of Small Molecules and the Electrical Properties of Membranes
Chapter 12 Intracellular Compartments and Protein Sorting
Chapter 13 Intracellular Vesicular Traffic
Chapter 14 Energy Conversion: Mitochondria and Chloroplasts
Chapter 15 Cell Communication
Chapter 16 The Cytoskeleton
Chapter 17 The Cell Cycle and Programmed Cell Death
Chapter 18 The Mechanics of Cell Division

V. Cells in Their Social Context
Chapter 19 Cell Junctions, Cell Adhesion, and the Extracellular Matrix
Chapter 20 Germ Cells and Fertilization
Chapter 21 Development of Multicellular Organisms
Chapter 22 Histology: The Lives and Deaths of Cells in Tissues
Chapter 23 Cancer
Chapter 24 The Adaptive Immune System
Chapter 25 Pathogens, Infection, and Innate Immunity