Organic Chemistry - 6th edition

Paula Yurkanis Bruice was raised primarily in Massachusetts, Germany, and Switzerland and was graduated from the Girls' Latin School in Boston. She received an A.B. from Mount Holyoke College and a Ph.D. in chemistry from the University of Virginia. She received an NIH postdoctoral fellowship for study in biochemistry at the University of Virginia Medical School, and she held a postdoctoral appointment in the Department of Pharmacology at Yale Medical School.

She is a member of the faculty at the University of California, Santa Barbara, where she has received the Associated Students Teacher of the Year Award, the Academic Senate Distinguished Teaching Award, and two Mortar Board Professor of the Year Awards. Her research interests concern the mechanism and catalysis of organic reactions, particularly those of biological significance. Paula has a daughter and a son who are physicians and a son who is a lawyer. Her main hobbies are reading mystery/suspense novels and her pets (three dogs, two cats, and a parrot).

Table of Contents
Ch. 1 Electronic Structure and Bonding, Acids and Bases 1
Ch. 2 An Introduction to Organic Compounds: Nomenclature, Physical Properties, and Representation of Structure 51
Ch. 3 Reactions of Alkenes. Thermodynamics and Kinetics 105
Ch. 4 Stereochemistry: The Arrangement of Atoms in Space; The Stereochemistry of Addition Reactions 178
Ch. 5 Reactions of Alkynes 242
Ch. 6 Electron Delocalization, Resonance, and Aromaticity 268
Ch. 7 Reactions of Dienes 310
Ch. 8 Reactions of Alkanes: Radicals 341
Ch. 9 Substitution and Elimination Reactions at an sp[superscript 3]-Hybridized Carbon I: The Halogen Leaving Group 368
Ch. 10 Substitution and Elimination Reactions at an sp[superscript 3]-Hybridized Carbon II: Leaving Groups Other Than Halogen. Organometallic Compounds 437
Ch. 11 Oxidation-Reduction Reactions 483
Ch. 12 Identification of Organic Compounds by Mass Spectrometry and Infrared Spectroscopy 521
Ch. 13 Reactions of Benzene and Substituted Benzenes 564
Ch. 14 Identification of Organic Compounds by NMR Spectroscopy and Ultraviolet/Visible Spectroscopy 633
Ch. 15 Carbonyl Compounds I: Reactions of Carboxylic Acids and Their Derivatives with Oxygen and Nitrogen Nucleophiles 706
Ch. 16 Carbonyl Compounds II: Reactions of Carbonyl Compounds with Carbon and Hydrogen Nucleophiles. Reactions of Aldehydes and Ketones with Oxygen and Nitrogen Nucleophiles. Reactions of [alpha],[beta]-Unsaturated Carbonyl Compounds 763
Ch. 17 Carbonyl Compounds III: Reactions at the [alpha]-Carbon 816
Ch. 18 Carbohydrates 870
Ch. 19 Heterocyclic Compounds 911
Ch. 20 Pericyclic Reactions 949
Ch. 21 Multistep Organic Synthesis 979
Ch. 22 Synthetic Polymers 1011
Ch. 23 Amino Acids, Peptides, and Proteins 1043
Ch. 24 Catalysis 1089
Ch. 25 The Organic Mechanisms of the Coenzymes 1125
Ch. 26 Lipids 1168
Ch. 27 Nucleosides, Nucleotides, and Nucleic Acids 1199
Ch. 28 The Organic Chemistry of Drugs: Discovery and Design 1244
App. I Physical Properties of Organic Compounds A
App. II pK[subscript a] Values A-7
App. III Derivations of Rate Laws A-9
App. IV Summary of Methods Used to Synthesize a Particular Functional Group A-12
App. V Spectroscopy Tables A-16
App. VI The Glycolytic Cycle and the Krebs Cycle A-22
Answers to Selected Problems A-24
Glossary G-1
Index I-1