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Statistics and the Life Sciences.
Examples and Overview.
2. Description of Populations and Samples
Frequency Distributions: Techniques for Data.
Frequency Distributions: Shapes and Examples.
Descriptive Statistics: Measures of Center.
Measures of Dispersion.
Effect of Transformation of Variables (Optional).
Samples and Populations: Statistical Inference.
3. Random Sampling, Probability, and the Binomial Distribution
Probability and the Life Sciences.
Introduction to Probability.
The Binomial Distribution.
Fitting a Binomial Distribution to Data (Optional).
4. The Normal Distribution
The Normal Curves.
Areas Under a Normal Curve.
The Continuity Correction (Optional).
5. Sampling Distributions
Illustration of the Central Limit Theorem (Optional).
The Normal Approximation to the Binomial Distribution (Optional).
6. Confidence Intervals
Standard Error of the Mean.
Confidence Interval for u.
Planning a Study to Estimate u.
Conditions for Validity of Estimation Methods.
Confidence Interval for a Population Proportion.
Perspective and Summary.
7. Comparison of Two Independent Samples
Standard Error of (y1 - y2).
Confidence Interval for (u1 - u2).
Hypothesis Testing: The t-test.
Further Discussion of the t-test.
More on Interpretation of Statistical Significance.
Planning for Adequate Power (Optional).
Student's t: Conditions and Summary.
More on Principles of Testing Hypotheses.
The Wilcoxon-Mann-Whitney Test.
8. Statistical Principles of Design
Restricted Randomization: Blocking and Stratification.
Levels of Replication.
Sampling Concerns (Optional).
9. Comparison of Two Paired Samples
The Paired-Sample t-Test and Confidence Interval.
The Paired Design.
The Sign Test.
Further Considerations in Paired Experiments.
10. Analysis of Categorical Data
Inference for Proportions: The Chi-Square Goodness-of-Fit Test.
The Chi-Square Test for the 2 X 2 Contingency Table.
Independence and Association in a 2 X 2 Contingency Table.
Fisher's Exact Test (Optional).
The r x k Contingency Table.
Applicability of Methods.
Confidence Interval for a Difference Between Proportions.
Paired Data and 2 X 2 Tables (Optional).
Relative Risks and the Odds Ratio (Optional).
Summary of Chi-Square Tests.
11. Comparing the Means of k Independent Samples
The Basic Analysis of Variance.
The Analysis of Variance Model (Optional).
The Global F Test.
Applicability of Methods.
Linear Combinations of Means (Optional).
Multiple Comparisons (Optional).
12. Linear Regression and Correlation
The Fitted Regression Line.
Parametric Interpretation of Regression: The Linear Model.
Statistical Inference Concerning B1.
Guidelines for Interpreting Regression and Correlation.
Summary of Formulas.
13. A Summary of Inference Methods
Data Analysis Samples.
Answers to Selected Exercises.
Index of Examples.
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