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Basic and Clinical Biostatistics - Text Only

Basic and Clinical Biostatistics - Text Only - 4th edition

Basic and Clinical Biostatistics - Text Only - 4th edition

ISBN13: 9780071410182

ISBN10: 007141018X

Basic and Clinical Biostatistics - Text Only by Beth Dawson and Robert Trapp - ISBN 9780071410182
Cover type: Paperback
Edition: 4TH 04
Copyright: 2004
Publisher: McGraw-Hill Publishing Company
International: No
Basic and Clinical Biostatistics - Text Only by Beth Dawson and Robert Trapp - ISBN 9780071410182

ISBN13: 9780071410182

ISBN10: 007141018X

Cover type: Paperback
Edition: 4TH 04

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A comprehensive user-friendly introduction to biostatistics and epidemiology applied to medicine, clinical practice, and research. Features "Presenting Problems" (case studies) drawn from studies published in the medical literature

Table of Contents

Table of Contents

1. Introduction to Medical Research

The Scope of Biostatistics & Epidemiology
Biostatistics in Medicine
The Design of This Book
The Organization of This Book
Additional Resources

2. Study Designs in Medical Research

Classification of Study Designs
Observational Studies
Experimental Studies or Clinical Trials
Meta-Analysis & Review Papers
Advantages & Disadvantages of Different Study Designs

3. Summarizing Data & Presenting Data in Tables & Graphs

Purpose of the Chapter
Scales of Measurement
Summarizing Numerical Data with Numbers
Displaying Numerical Data in Tables & Graphs
Summarizing Nominal & Ordinal Data with Numbers
Tables & Graphs for Nominal & Ordinal Data
Describing Relationships Between Two Characteristics
Graphs for Two Characteristics
Examples of Misleading Charts & Graphs
Computer Programs

4. Probability & Related Topics for Making Inferences About Data

Purpose of the Chapter
The Meaning of the Term "Probability"
Populations & Samples
Random Variables & Probability Distributions
Sampling Distributions
Estimation & Hypothesis Testing

5. Research Questions About One Group

Purpose of the Chapter
Mean in One Group When the Observations Are Normally Distributed
Hypothesis Testing
Research Questions About a Proportion in One Group
Means When the Same Group Is Measured Twice
Proportions When the Same Group Is Measured Twice
What to Do When Observations Are Not Normally Distributed
Mean Differences When Observations Are Not Normally Distributed
Finding the Appropriate Sample Size for Research

6. Research Questions About Two Separate or Independent Groups

Purpose of the Chapter
Decisions About Means in Two Independent Groups
Decisions About Proportions in Two Independent Groups
Finding Sample Sizes for Means and Proportions in Two Groups

7. Research Questions About Means in Three or More Groups

Purpose of the Chapter
Intuitive Overview of ANOVA
Traditional Approach to ANOVA
Multiple-Comparison Procedures
Additional Illustrations of the Use of ANOVA
Nonparametric ANOVA
Comparing Frequencies or Proportions in More than Two Groups
Sample Sizes for ANOVA

8. Research Questions About Relationships Among Variables

An Overview of Correlation & Regression
Comparing Two Correlation Coefficients
Other Measures of Correlation
Linear Regression
Use of Correlation & Regression
Sample Sizes for Correlation & Regression

9. Analyzing Research Questions About Survival

Purpose of the Chapter
Why Specialized Methods Are Needed to Analyze Survival Data
Actuarial, or Life Table, Analysis
Kaplan--Meier Product Limit Method
Comparing Two Survival Curves
The Hazard Function in Survival Analysis
Interpreting Survival Curves from the Literature
The Intention-to-Treat Principle

10. Statistical Methods for Multiple Variables

Purpose of the Chapter
Multiple Regression
Controlling for Confounding
Predicting Nominal or Categorical Outcomes
Predicting a Censored Outcome: Cox Proportional Hazard Model
Methods for Classification
Multiple Dependent Variables
Summary of Advanced Methods

11. Survey Research

The Research Questions
Questionnaire Layout
Reliability and Validity of Survey Instruments
Administration of Surveys
Selecting the Sample & Determining N
Analysis of Survey Results

12. Methods of Evidence-Based Medicine and Decision Analysis

Evaluating Diagnostic Procedures with the Threshold Model
Measuring the Accuracy of Diagnostic Procedures
Using Sensitivity & Specificity to Revise Probabilities
ROC Curves
Decision Analysis
Using Decision Analysis to Compare Strategies
Using Decision Analysis to Evaluate Timing & Methods
Computer Programs for Decision Analysis

13. Reading the Medical Literature

Purpose of the Chapter
Review of Major Study Designs
The Abstract & Introduction Sections of a Research Report
The Method Section of a Research Report
The Results Section of a Research Report
The Discussion & Conclusion Sections of a Research Report
A Checklist for Reading the Literature
Appendix A Tables
Appendix B Answers to Exercises
Appendix C Flowcharts for Relating Research Questions to Statistical Methods

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